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KMID : 0377619690160020157
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Korean Jungang Medical Journal
1969 Volume.16 No. 2 p.157 ~ p.162
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Studies on the Effect of Streptomycin on the Klebsiella Phage-Host Cell, System
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Abstract
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The phage growth in host bacteria was inhibited by the sub-bacteriostatic dose of streptomycin (SM) added at the latent period of phage and, the earlier the adding time of SM was, the more remarkable became the inhibiting grade. The SM, however, introduced at the late latent period did not show any influence to the phage growth.
The phage adsorbed to host bacteria for 10 minutes at 37°C multiplicated a little even though the bacterial growth is inhibited by SM.
The higher the grade of SM resistance of host bacteria was, the lower became the grade of phage growth. The appearance of multiplication, in normal host bacteria, of the phage passed through the SM resistant-host cells was much different from that showed in SM resistant-host cells.
A small dose of SM did not give any special influence to the phage growth in SM resistant-host bacteria.
The character of phage was a little changed by passing through the SM resistant-host bacteria.
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KEYWORD
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